Hypoglycemic Effects of Punarnava (Boerhaavia diffusa) | Chapter 6 | Innovations in Biological Science Vol. 1

 This study aims to review the antidiabetic effect of Boerhaavia diffusa. Diabetes is a life style disorder that would affect 439 million people globally by 2030. The incidence of diabetes, a metabolic disorder, is increasing at a very rapid pace globally but hypoglycemic drugs like insulin, bioguanides, thiazolidiones and sulphonylureas, which produce several adverse side effects, are still the main stay for its treatment. However, the traditional medicines derived from plants have lesser side effects and are of low cost. Boerhaavia diffusa,  belonging to Nyctaginaceae family, also known as Punarnava, has great               many medicinal properties and is one of the oldest medicines described  in Ayurveda for the treatment of a number of diseases including diabetes. B. diffusa has been reported to be diuretic, anti-inflammatory, anticonvulsant, antifibrolytic, antibacterial, antidiabetic, hepatoprotective, immunosuppressive, nephroprotective, antiasthamatic, antihelminitic, etc. It contains alkaloids, flavanoids, lipids, carbohydrates, steroids, lignins, proteins, triterpeniods, glycoproteins, β-sitosterol, α-2-sitosterol, ester of β-sitosterol, palmitic acid, β-ecdyosone, hexacosanoic, tetracosanoic, arachidonic and     stearic acids, etc., which might be responsible for its curative properties.  Further reviews need to focus on extensive biochemical and molecular investigations in order to identify the active compounds concerned with the hypoglycemic effect.

Author(s) Details:

Dr. Sweta Arora,
Pineal Research Laboratory, Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi – 221005, Uttar Pradesh, India and Kalinga Institute of Social Sciences (Deemed University), Bhubaneswar- 751024, Odisha, India.

Dr. Priyoneel Basu,
Kalinga Institute of Social Sciences (Deemed University), Bhubaneswar- 751024, Odisha, India.

Mantu Meher,
Kalinga Institute of Social Sciences (Deemed University), Bhubaneswar- 751024, Odisha, India.

Sambid Sunamajhi,
Kalinga Institute of Social Sciences (Deemed University), Bhubaneswar- 751024, Odisha, India.


Please see the link here: https://stm.bookpi.org/IBS-V1/article/view/14015

Herbal Approaches towards Diabetes | Book Publisher International

 Diabetes is a disease that occurs when the blood glucose level is too high in the body. It develops when the pancreas doesn’t make enough insulin in the body. Diabetes is a major cause of some diseases like blindness, kidney failure, neurological disorders, heart attack etc.  More than half a billion people are living with diabetes in the world.  It affects men, women and children of all ages in every country. Diabetes is a growing challenge in India with an estimated 8.7% diabetic population in the age group of 20 and 70 years. Diabetes has several forms; type 2 is the most common. A combination of treatment strategies can help manage the condition to live a healthy life and prevent various complications caused by diabetes. Herbal medicinal plants have therapeutically important phytochemical constituents which is potential in the treatment of diabetes as well as other diseases. Terpenes, tannins, saponins and alkaloids are important bioactive phytoconstituents for antidiabetic properties. Herbal medicines are gaining importance and people turn towards herbal medicine due to cost- effective, improved therapeutic effects with lesser side effects.

This book “herbal approaches towards diabetes” provides useful information about diabetes, types of diabetes, diabetes - associated complication and management by different medicinal plants. This book also presents the antihyperglycemic activity of various extracts of some medicinal plants (Bambusa vulgaris and Neolamarckia cadamba was studied in streptozotocin - induced diabetes rats. This book also presents the antihyperglycemic activity of various extracts of some medicinal plants Woodfordia fruticosa, Zizyphus Jujube and Carissa spinarum were studied in alloxon induced diabetic rats. The study was carried out in normal animals. Studies revealed that plants shown significant antidiabetic activity.

This book provides the scope for the readers to know the knowledge and management of diabetes by herbal approaches. It can be helpful to researchers to further explore the active constituents of antidiabetic plants and their possible mechanism for future research.

Author(s) Details:

Neeli Rose Beck,
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, India.

Dimpi Dewangan,
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, India.

Rishika Gupta,
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, India.

Sourabh Ghosh,
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, India.

Please see the link here: https://stm.bookpi.org/HATD/article/view/12491

Study on Transient Adenocorticotropic Hormone Deficiency in an Infant | Chapter 16 | Issues and Developments in Medicine and Medical Research Vol. 8

 Background: Adenocorticotropin Hormone (ACTH) deficiency is a rare condition marked by secondary adrenal insufficiency with low or nonexistent cortisol production, adequate pituitary hormone release, and the absence of anatomical pituitary abnormalities.

The purpose of this study is to describe a premature newborn who was found to have a transitory ACTH deficit.

Summary of the Case: The patient was the result of a clomiphen-induced 28-week pregnancy in a 40-year-old gestational diabetic mother. He was ventilated for 30 days and diagnosed with Retina of Prematurity, Grade IV (ROP). He had recurrent hypoglycemia crises, with blood sugar levels of 1.6 mmol/L, low serum cortisol levels of 65 nmol/L (normal; 150-630), and ACTH levels of 1.5 pmol/L (normal; 1.6-13.9), as well as suppressed serum insulin and normal thyroid, growth hormone, and gonadal activities. The results of the magnetic resonance imaging (MRI) were unremarkable. He was started on 2.5 mg of hydrocortisone twice a day for two years, then gradually tapered and terminated. With a normal shot ACTH stimulation test, serum cortisol was 175 nmol/L and ACTH was 5.5 pmol/L.

Conclusions: This premature baby's recurring hypoglycemia was caused by an individual ACTH deficit that was found to be temporary. The existence of such a disorder must be known to paediatricians.

Author(S) Details

Nasir A. M. Al Jurayyan
Department of Pediatrics, College of Medicine and King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia.

Sharifah D. A. Al Issa
Department of Pediatrics, College of Medicine and King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia.

Rushaid N. A. Aljurayyan
Radiology and Medical Imaging, College of Medicine and King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia.

View Book:- https://stm.bookpi.org/IDMMR-V8/article/view/5813