Refractory Heart Failure | Chapter 2 | Medicine Essentials in Clinical Practice

Heart failure is a multifaceted clinical condition arising from structural or functional abnormalities that hinder the heart's capacity to fill with or pump blood effectively. The 2022 guidelines from the AHA/ACC/HFSA introduce a staging framework that classifies patients based on their clinical symptoms and disease progression. This study thoroughly examines the impact of heart failure and explores management strategies tailored to the different stages of the condition. It highlights pharmacological approaches for symptom management and cardiac remodeling, alongside interventional therapies and advanced devices such as Implantable Cardiac Defibrillators, Cardiac Resynchronization Therapy, and Left Ventricular Assist Devices.

 

Author (s) Details

 

Rohit Raina
Department of General Medicine, AIIMS Bathinda, Punjab- 151001, India.

 

Preeti Singh Dhoat
Department of General Medicine, AIIMS Bathinda, Punjab- 151001, India.

 

Niket Verma
Department of General Medicine, AIIMS Bathinda, Punjab- 151001, India

 

Barath G.R
Department of General Medicine, AIIMS Bathinda, Punjab- 151001, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/mono/978-93-49238-92-3/CH2

Assessment of Responsiveness to Cardiac Resynchronization Therapy: A Novel and Simple Exercise Approach | Chapter 12 | Current Innovations in Medicine and Medical Science Vol. 3

 In this work, the heart rate recovery indicator( HRRI), a new exercise test parameter, was estimated as a implicit predictor of cardiac resynchronization remedy response( CRT). We hypothecate that ET may be practical and applicable to study by assaying the time rate between the acceleration and retardation of heart rate. Following implantation and every six months after that, cases who entered a CRT device successively were covered. The minimum and maximum heart rates, as well as the acceleration and retardation ages, were used to measure an trouble test( ET). The rate of acceleration to retardation time( AT/ DT), or HRRI, was calculated and compared to the result. We used logistic retrogression to assess the prophetic value of HRRI for askers andnon-responders to CRT. The area under the wind( AUC) was reckoned to distinguish between positive and negative issues. A aggregate of 109 cases( 74 men, mean age63.3 ±9.8 times) were anatomized; endless long- term emulsion CRT pacing was possible in 65 cases. Cases were assigned to two groups askers andnon-responders(98/11 cases). During a mean follow- up of 36 months, 545 ETs were performed. HRRI was significantly advanced in askers versusnon-responders(3.16 ± 2vs.1.4 ±0.5, p<0.001). The optimal arrestment value for HRRI as a predictor of CRT response was1.51( area under the receiver operating characteristic( ROC) wind = 0.844). Askers had significant left- ventricular( LV) rear redoing( LV end- diastolic volume = 240 ± 90 mLvs. 217 ± 89 mL, p<0.001) and advanced LV ejection bit( 26 ±5.8vs. 35 ±8.7, p<0.001). HRRI calculation during routine ET is useful for the evaluation of responsiveness to CRT. The present study is the first to estimate a new parameter HRRI using HR geste after conclusion of exercise in cases with CRT; birth and minimal HR couldn't prognosticate CRT response, but the analysis of ET graphs in askers versusnon-responders showed a better outgrowth corelated with advanced response in heart HRR.

Author(s) Details:

Alina-Ramona Cozlac,
Department of Cardiology, “Victor Babes” University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania and Department of Cardiology, Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania.

Lucian Petrescu,
Department of Cardiology, “Victor Babes” University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania and Department of Cardiology, Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania.

Simina Crisan,
Department of Cardiology, “Victor Babes” University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania and Department of Cardiology, Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania.

Constantin Tudor Luca,
Department of Cardiology, “Victor Babes” University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania and Department of Cardiology, Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania.

Cristina Vacarescu,
Department of Cardiology, “Victor Babes” University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania and Department of Cardiology, Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania.

Caius Glad Streian,
Department of Cardiology, “Victor Babes” University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania and Department of Cardiology, Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania.

Andra Gurgu,
Department of Cardiology, “Victor Babes” University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania.

Angela Dragomir,
Department of Cardiology, “Victor Babes” University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania and Department of Cardiology, Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania.

Emilia Violeta Goanta,
Department of Cardiology, “Victor Babes” University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania.

Radu Vatasescu,
Department of Cardio-Thoracic Pathology, “Carol Davila” University of Medicine and Pharmacy, Dionisie Lupu Street, no. 37, Sector 2, 020021 Bucharest, Romania and Department of Cardiology, Clinical Emergency Hospital Bucharest, 8 Calea Floreasca, 014461 Bucharest, Romania.

Kandara Mohamed Chahine,
Department of Cardiology, “Victor Babes” University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania.

Ciprian Rachieru,
Department of Cardiology, “Victor Babes” University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania and Department of Internal Medicine, County Emergency Hospital, 5 Gheorghe Dima Street, 300079 Timisoara, Romania.

Dragos Cozma,
Department of Cardiology, “Victor Babes” University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania and Department of Cardiology, Institute of Cardiovascular Diseases Timisoara, 13A Gheorghe Adam Street, 300310 Timisoara, Romania.

Please see the link here: https://stm.bookpi.org/CIMMS-V3/article/view/8386

A Comparative Research on Conservative and Device Treatments in Chronic Heart Failure | Chapter 1 | Highlights on Medicine and Medical Research Vol. 8

 Chronic heart failure (CHF) is a significant public health issue for the entire world, since it is a very common disease that sometimes leads to life-threatening illness and has a high risk and mortality rate [1]. Our aim is to look at what has been accomplished in recent years in the care of CHF patients with a left ventricular ejection fraction (LVEF) of less than 40%. BNP has recently been discovered to be essential in the pathogenesis of heart disease. As a result, we attempted to examine the outcomes of a complex medical treatment procedure in CHF patients using a combination of sacubitril and valsartan, which is an angiotensin receptor neprilysin inhibitor. The system treatment methods used in the treatment of these patients, especially cardiac resynchronization therapy, were also investigated (CRT). Finally, we compared the outcomes of a complex medical treatment procedure using a combination of sacubitril and valsartan, which is an angiotensin receptor neprilysin inhibitor, to those of cardiac resynchronization therapy. Patients who are handled in this manner (with CRT) are forced to stop working, even if only for a short time. Furthermore, CRTs are much more costly than traditional medicine.

Author (s) Details

Eyubova Ulviyya Aladdin
Department of III Internal Diseases, Azerbaijan Medical University, Baku, Azerbaijan.

View Book :- https://stm.bookpi.org/HMMR-V8/article/view/818