Cardiac Arrest (CA) as the Initial Presentation of Cocaine-induced Takotsubo Cardiomyopathy (TCM): Clinical Findings and Treatments | Chapter 3 | Medicine and Medical Research: New Perspectives Vol. 7

 

A unique case report of a 54-year-old male who developed Takotsubo cardiomyopathy (TCM) following recent cocaine use presenting with cardiac arrest (CA) has been presented. Cocaine is a sympathomimetic agent that acts by inhibiting the reuptake of norepinephrine, dopamine, and serotonin through binding with each transporter resulting in an accumulation of these neurotransmitters in the postsynaptic terminal. Cocaine is used as an illicit substance responsible for the most common cause of drug-related death. It is a stimulant that acts on the sympathetic nervous system and cardiovascular system leading to exaggerated, prolonged sympathetic activity due to the accumulation of neurotransmitters. Congestive heart failure, myocarditis, arrhythmias, and coronary artery spasms are among the cardiovascular adverse effects of cocaine. In the absence of obstructive coronary artery disease, takotsubo cardiomyopathy (TCM) is characterized by transitory akinesis, dyskinesis, or hypokinesis of the left ventricular (LV) wall with or without apical involvement. Cocaine-induced TCM is an extremely rare condition emphasizing the need for its prompt diagnosis by physicians. A case report of a 54-year-old male brought to the emergency department (ED) after an out-of-hospital cardiac arrest (CA), found to have TCM in the setting of cocaine use, has been presented. Clinicians need to understand the association between cocaine use and the development of TCM as cardiomyopathy of this type can result in complete remission after discontinuing the offending agent. There are no standardized recommendations for pharmacological treatment and prevention of episodes of TCM and further studies/trials need to be done to answer questions regarding the clinical diagnostic criteria, etiology, pathophysiology, and management of this syndrome.

 

Categories: Cardiology, Internal Medicine, Substance Use and Addiction.

 

Author (s) Details

Catherina Almalouf

Internal Medicine, Brookdale University Hospital Medical Center, Brooklyn, USA and Internal Medicine, St. George's University School of Medicine, Brooklyn, USA.

 

Narek Hakobyan
Internal Medicine, Brookdale University Hospital Medical Center, Brooklyn, USA.

 

 

Vivek Yadav
Pulmonary and Critical Care, State University of New York Downstate Health Sciences University, New York, USA.

 

Anjula Gandhi
Internal Medicine, Brookdale University Hospital Medical Center, Brooklyn, USA.

 

Ruchi Yadav
Internal Medicine, Brookdale University Hospital Medical Center, Brooklyn, USA.

 

Please see the book here:- https://doi.org/10.9734/bpi/mmrnp/v7/1993

Diminution of Electrical Systole of Heart among Patients: A Review | Chapter 10 | Novel Research Aspects in Medicine and Medical Science Vol. 2

 In this unit, it is mention one of various electrical cardiac irregularities called “the closeness of short PR and QTc intervals together in the unchanging ECG tracing.” ALSO CALLED “BREIJO’s MODEL (cause it was Prof. Breijo-Marquez who described it for the first come into sight 2007). The human heart is an tool that has to work constantly at a repetitiveness of between 60 and 90 phases per minute) to keep you awake, and it has to be trustworthy and effective. To do this, it depends a specialized network of containers called the cardiac broadcast system. It’s as known or named at another time or place heart’s energetic system. Morbidity and a off-course range of symptoms, from minor to those requiring next attention on account of the possibility of unexpected cardiac death, are precipitated by changes in the cardiac electrical method. Atrial fibrillation, which is ultimate common (even though it is ‘always pronounced’ that it is the most universal, this is not correct, the most low alteration of the cardiac energetic system is SYNUSAL TACHYCARDIA, the Atrial fibrillation only is ultimate common symptomatic arrhythmia..) of these energetic abnormalities, should more common as the average human age rises. A cardiac calibrator was secondhand by four different cardiologists in confuse fashion to document a distinct ECG pattern, that of a short PR and QTc breaks together in the same ECG seeking (Breijo’s Model) from more than 25.0000 cases determined for this condition (more than two thousand five hundred cases judged since 2.007 to date). Here, in addition to descriptions of their syndromes and ancillary tests, we report the dispassionate characteristics of 3500 things with confirmed short PR and QTc intervals in the same ECG trace ((Breijo’s Model) ) . Before regarding a given type of ECG following as normal, it must be fully examined in things with doubtful symptoms.

Author(s) Details:

Francisco R. Breijo-Márquez,
East Boston Hospital, School of Medicine, 02136, Tremont ST. Boston Massachusetts, USA.

Please see the link here: https://stm.bookpi.org/NRAMMS-V2/article/view/11806