The intricate interplay between thyroid function, cirrhosis,
and liver dysfunction presents a compelling opportunity for scientific and
medical advancements. This exploration has multifaceted significance, with a
primary focus on revolutionizing clinical diagnosis. The research introduces a
promising avenue for novel diagnostic tools, utilizing thyroid function tests
to detect cirrhosis early—a groundbreaking prospect that minimizes the risk of
severe complications such as liver cancer and improves treatment outcomes.
Early diagnosis not only holds clinical benefits but also addresses the
economic burden associated with expensive liver transplants, often inaccessible
in countries with limited healthcare coverage. This research becomes a pivotal
force in reshaping clinical practice, fostering groundbreaking research, and
ultimately enhancing the health and well-being of individuals grappling with
these interconnected conditions.
All patients aged 30-80 years with cirrhosis of liver who are attending
Rajarajeshwari Medical College and Hospital. Detailed history, physical
examination and drug history was taken as per pre- designed performa. Relevant
investigations were done for assessing thyroid function and liver cirrhosis.
Severity of liver dysfunction was graded by using Child Pugh Scoring.
The prevalence of hypothyroidism among patients with liver cirrhosis was 64%.
Majority of the cases had a high TSH and TSH levels were directly correlated
severity of liver disease. Total T3 levels were low in majority of the cases
and it was inversely correlated with severity of liver disease. FT3 was low in
most of the cases with child B and child C score; it was inversely correlated
with severity of liver disease. FT3 was found to be a more sensitive marker
than total T3 for assessing severity of liver disease.
Thyroid dysfunction is widespread in cirrhosis of the liver, hence thyroid
function testing should be performed on all cirrhotic patients to assess the
severity and prognosis.
Author(s) Details:
Samarthana Vijaykumar,
Department of General Medicine, Rajarajeshawari Medical College and
Hospital, India.
Mamatha
B. Patil,
Department
of General Medicine, Rajarajeshawari Medical College and Hospital, India.
Please see the link here: https://stm.bookpi.org/ANUMS-V9/article/view/13632
