The Role and Biochemical Significance of Plant Secondary Metabolites | Chapter 5 | Natural Products Chemistry: From Discovery to Applications, Edition 1

Natural products can be reproduced in labs by chemical processes, since they adeptly replicate the complex bioactive molecules found in nature. This encompasses a synthesis of several repeats of one-pot synthetic methods to produce natural products or analogous structures, together with subsequent biological assays of the structure and the increasing pharmacological activity of the drug. Chemical synthesis is crucial for addressing the constraints posed by the limited availability of natural resources and their sustainable harvesting, in comparison to natural production. It also facilitates the creation of structural analogues that have enhanced biological activity or pharmacokinetic properties. This presentation highlights the significance of the chemical synthesis process in drug discovery, including medicinal chemistry and the development of novel therapeutics.

 

Author (s) Details

 

Shubhangee Agarwal
Department of Chemistry, School of Sciences, IFTM University, Moradabad-244102, Uttar Pradesh, India.

 

Priyanka Rani
Department of Chemistry, School of Sciences, IFTM University, Moradabad-244102, Uttar Pradesh, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/mono/978-93-48388-70-4/CH5 

The Ability of Different Lignins to Stabilize the Oil-in-water Emulsion | Chapter 8 | Advanced Aspects of Engineering Research Vol. 7

 The ability of aspen soda and wheat straw soda lignin to stabilise the “rapeseed oil-in-water” (O/W) emulsion was investigated, taking into account the pH value and concentration of the applied water solutions, as well as the lignin chemical composition and molecular mass, as well as the sizes and zeta potential of the lignin particles. The O/W emulsion stabilised with alkaline water solutions of wheat straw lignin revealed the maximum stability in alkaline medium, but the ability of aspen soda lignin to inhibit oil droplet coalescence presented itself across the pH range examined. The pH of the wheat straw lignin water solution drops as the pH drops. With the exception of the lignin increased concentrations in acidic medium, the decline in the separation volume of the O/W emulsion was minimal. By falling pH values and rising lignin content in the emulsion, the aggregative stability of the O/W emulsion, which was stabilised with aspen soda lignin, improved. The results showed that the electrostatic stabilisation mechanism was used to stabilise the O/W emulsion in alkaline lignin solutions, however in neutral and acidic media, the mechanism was more convoluted, with a growing role for lignin's ability to create interfacial polymeric films at the liquid/liquid interface. The stability of the O/W emulsion was compared, and aspen soda lignin was found to be a superior stabiliser than wheat straw lignin.

Author(s) Details

Galia Shulga
Laboratory of Lignin Chemistry, Latvian State Institute of Wood Chemistry, 27 Dzerbenes St., LV-1006, Riga, Latvia.

Sandra Livcha
Laboratory of Lignin Chemistry, Latvian State Institute of Wood Chemistry, 27 Dzerbenes St., LV-1006, Riga, Latvia.

Brigita Neiberte
Laboratory of Lignin Chemistry, Latvian State Institute of Wood Chemistry, 27 Dzerbenes St., LV-1006, Riga, Latvia.

Anrijs Verovkins
Laboratory of Lignin Chemistry, Latvian State Institute of Wood Chemistry, 27 Dzerbenes St., LV-1006, Riga, Latvia.

Sanita Vitolina
Laboratory of Lignin Chemistry, Latvian State Institute of Wood Chemistry, 27 Dzerbenes St., LV-1006, Riga, Latvia.

Elina Zhilinska
Laboratory of Lignin Chemistry, Latvian State Institute of Wood Chemistry, 27 Dzerbenes St., LV-1006, Riga, Latvia.

View Book :- https://stm.bookpi.org/AAER-V7/article/view/966