Showing posts with label Human colon cancer cell.. Show all posts
Showing posts with label Human colon cancer cell.. Show all posts

Tuesday, 11 January 2022

Green synthesis of Copper Oxide Nanoparticles Decorated with Graphene oxide for Anticancer Activity and Catalytic Applications: An Advanced Study Approach | Chapter 10 | New Innovations in Chemistry and Biochemistry Vol. 6

 Nanotechnology is a rapidly evolving field with many implications for medicine delivery. As haulers, nanoparticles considerably improve the capability of target-specific medicine delivery, and are consequently used in the treatment of dreadful diseases like cancer and diabetes. This boom's purpose was to make copper oxide nanoparticles (CuO-NPs) from Acalypha Indica leaf extract, which were subsequently mixed with graphene oxide (GO) to make GO-CuO nanocomposites. Second, examine CuO-NPs and GO-CuO nanocomposites' photocatalytic activity in the decolorization of methylene blue dye, as well as their activity against HCT-116 human colon cancer cell lines. The synthesised nanocomposites were characterised by FTIR, UV-vis, X-ray powder diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDAX), X-ray Photoelectron Spectroscopy (XPS), and transmission electron microscopy (TEM). According to photocatalytic experiments, synthesised nanocomposites breakdown methylene blue dye with an efficiency of 83.20 percent and exhibit a cytotoxic activity of 70% against HCT-116 human colon cancer cell lines at 100 g/ml. GO-CuO nanocomposites show substantial action against cancer cell lines as well as photocatalytic activity when compared to nanoparticles as a whole.



Author (S) Details

G. Kavitha
Department of Chemistry, College of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu-603203, India.

J. Vinoth Kumar
Department of Chemistry, College of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu-603203, India.

R. Arulmozhi
Department of Chemistry, College of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu-603203, India.

N. Abirami
Department of Chemistry, College of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu-603203, India.

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