Showing posts with label Bacterial biofilm. Show all posts
Showing posts with label Bacterial biofilm. Show all posts

Saturday, 21 January 2023

New Paradigm in Explaining Dry Socket: Case Studies| Chapter 7 | Perspective of Recent Advances in Medical Research Vol. 6

 Dry hole is considered as ultimate common complication following premolar extraction. It is principally manifested by harsh irradiating pain that start 1 to 4 days after dental distillation with a denuded cavity. Although many risk factors are guide it, no clear and direct cause has been specified to explain allure etiopathogenesis. Here, we suggest a new pathogenesis and management of Dry cavity based on new microbiological and dispassionate findings from 11 dispassionate cases.We present a series of 6 Dry cavity cases from which alveolar swabs have been captured for microbial exploration. Materials from the 6 cases were assign bacterial culture and susceptibleness testing. Microbiological results granted the presence of Pseudomonas aeruginosa in 4 samples. Furthermore, the antibiogram showed nervousness to ciprofloxacin.Then, a serial of 11 cases opposing to local management, were doctored by ciprofloxacin that was prescribed at 500 mg 3 periods per day for 5 days. After taking medicines,9 patients knowledgeable complete relief in 12 to 24 hours. In addition to former laboratory data, this dispassionate outcome lends better credence to the plan that an infectious means contributes to the pathophysiology of Dry socket.

Author(s) Details:

Wael Khalil,
Lebanese University, Lebanon.

Please see the link here: https://stm.bookpi.org/PRAMR-V6/article/view/9152

Tuesday, 19 October 2021

A Review on Resistance Mechanisms in Bacterial Biofilm Formations | Chapter 2 | Recent Developments in Medicine and Medical Research Vol. 3

 The goal of this review is to present the mechanisms that lead to antimicrobial treatment resistance in bacterial biofilms. Biofilm-forming bacteria are the source of chronic and recurrent illnesses. Joint prosthesis, intravenous catheters and stents, endotracheal tubes, and cardiovascular devices are also susceptible. The issue is massive since it leads to higher hospitalisation bills, frequent operations, and longer antibiotic use. Bacterial biofilms have different resistance mechanisms than planktonic cells. The following are some of them: Glycocalyx and extracellular polymeric substances (EPS), enzyme-mediated antibiotic resistance, cell heterogeneity in metabolism and growth rate, persister cells, genetic adaptation and mutations, efflux pumps, adverse environmental conditions, outer membrane structure, bacteriophages, interactions between different types of bacteria in polymicrobial biofilms The type of microorganism determines whether mechanism or combination of processes is used. As a result, a better understanding of their function will aid in discovering ways to combat the dangerous illnesses produced by biofilms.

  Author (S) Details Nikiforos Rodis

Medical School, Democritus University of Thrace, Greece.

Vasiliki Kalouda Tsapadikou

Medical School, Democritus University of Thrace, Greece.

Charalampos Potsios

Department of Internal Medicine, University General Hospital of Patras, Greece.

Panagiota Xaplanteri

Department of Microbiology, University General Hospital of Patras, Greece.