Intraoral Lipoma of Palate | Chapter 5 | Current Innovations in Medicine and Medical Science Vol. 3

 Lipomas are the most frequent benign soft towel tumours in the body, yet they're veritably uncommon in the oral depression. Whenever they're seen in oral depression; buccal mucosa, bottom of mouth and lingo are the most generally affected. Intraoral lipomas are characterised by benign, well- reprised swelling that's effortless and has a unheroic colour. We present a case of an intraoral lipoma in which a 22- time-old girl came with a single well- reprised blowup in the posterior region of the palate on the left side. The purpose of this book chapter is to emphasise the need for dentists to be apprehensive of frequence of circumstance of intraoral lipoma so that prompt operation can be done for the oral pathologies.

Author(s) Details:

Priyanka Tidke,
Department of Oral Medicine and Radiology, MGM Dental College and Hospital, Navi Mumbai, Maharashtra, India.

Vikas Desai,
Department of Dentistry, Shri. B.M Patil Medical Colege & Research Centre, Vijayapura, Karnataka, India.

Prashant Munde,
Department of Oral Pathology and Microbiology, Aditya Dental College, Beed, Maharashtra, India.

Please see the link here: https://stm.bookpi.org/CIMMS-V3/article/view/8379

Study on Adipocytes as Sensors of Lipid Transport through Caco-2/HT29-MTX Intestinal Barrier Rescued from Cancer Phenotype by Oleic Acid | Chapter 7 | Recent Research Advances in Biology Vol. 11

 Nutrients and many medications enter the body through the gastrointestinal epithelium, which is a one-of-a-kind route. The goal of this work was to see if co-culturing two colon cancer cell lines, HT29-MTX mucus-producing cells and Caco-2 enterocyte-like cells, improved differentiation into a functioning in vitro intestinal barrier model. Real-time studies, immunochemistry, and gene expression analysis on Caco-2 vs co-cultures of Caco-2 and HT29-MTX (10%) cells were used to validate the findings. The partial preservation of cancer-cell phenotype in differentiated Caco-2 cells was confirmed, and fatty acids were grouped together as putative cancer signalling regulators. HT29-MTX cells caused morphological changes in Caco-2 cells, increased their proliferation rate slightly, and significantly altered gene transcription of phenotype markers, fatty acid receptors, intracellular transporters, and lipid droplet components, as well as their functional responses to oleic acid. In vitro, co-culture of cancer cells with goblet cells partially restored enterocyte phenotype, which was completed by oleic acid interaction with cancer cell signalling pathways. The lipid transport of a rebuilt gastrointestinal epithelium was studied. The ability of adipose tissue to regulate lipemia is strongly reliant on nutrition absorption in the intestine. adipocytes as lipid sensors for absorption The rebuilt intestinal barrier was pre-absorbed with oleic acid (OA). With partially differentiated 3T3L1-MBX adipocytes detecting up to 5 M OA in solution or 40 M OA pre-absorbed by Caco2/HT29-MTX intestinal barriers, optimised experimental conditions for co-culture with intestinal barriers were obtained. The ability to accumulate TG in adipocytes was substantially impacted by metabolism, particularly glycemia and insulinemia. The current study shows that Caco2/HT29-MTX intestinal barriers operate substantially better for fatty acid uptake and release than Caco-2 intestinal barriers. These findings, taken collectively, open up new avenues for research.

Author (S) Details

Emmanuelle Berger
University of Lyon, UMR Ecologie Microbienne Lyon (LEM), CNRS 5557, INRAE 1418, Université Claude Bernard Lyon 1, VetAgro Sup, Research Team “Bacterial Opportunistic Pathogens and Environment” (BPOE), 69622 Villeurbanne, France.

Research Director, Alain Géloën
University of Lyon, UMR Ecologie Microbienne Lyon (LEM), CNRS 5557, INRAE 1418, Université Claude Bernard Lyon 1, VetAgro Sup, Research Team “Bacterial Opportunistic Pathogens and Environment” (BPOE), 69622 Villeurbanne, France.

View Book :- https://stm.bookpi.org/RRAB-V11/article/view/2146

A Rare Case of Intraoral Palatal Lipoma | Chapter 13 | Highlights on Medicine and Medical Science Vol. 2

 Lipomas are the most common benign neoplasms that develop in the human body from adipose cells. Intraoral lipomas are extremely rare, accounting for less than 5% of all head and neck cancers. Nonetheless, lipoma should be considered as a differential diagnosis for swellings of the oral cavity. The mainstay of treatment for intraoral lipoma is surgical excision. Due to the abundance of fat, the buccal mucosa is the most common site of an intraoral lipoma, followed by the tongue, lips, floor of the mouth, and gingiva, with the palate being the rarest due to a lack of adipose tissue. In this case study, the lipoma was found to have originated from the soft palate. To determine a definitive diagnosis, it was surgically excised in its entirety and histopathological examinations were performed. This case is being documented because an intraoral lipoma is unusual, and even more so when it occurs in the palate.

Author(s) Details

Dr. Anuya Satyaprakash Gupta
Department of E.N.T., Symbiosis Medical College for Women & Symbiosis University Hospital and Research Centre, Symbiosis International University (SIU), Lavale, Pune, India.

Dr. Girija Amit Ghate
Department of E.N.T., Dr. D. Y. Patil Medical College, Hospital & Research Centre, Pimpri, Pune, India.

View Book :- https://stm.bookpi.org/HMMS-V2/article/view/1359