Background:
Rhinosporidiosis is a rare chronic disease caused by Rhinosporidium seeberi,
mainly affecting the nasal and conjunctival mucosa. The diagnosis is made
through histopathological examination. The disease is endemic to the Indian
subcontinent, with few cases described in Brazil. Thus, this study aimed to
describe clinical and histopathological aspects of rhinosporidiosis in an area
of northeastern, Brazil. Methods: To
identify the clinical and histopathological characteristics, a retrospective
study was carried out on 21 patients diagnosed with rhinosporidiosis at the
Presidente Dutra University Hospital during 10 years. The data are obtained
from medical records and review of histological slides of each case. Results: In this study, most of the patients
were men (80.00%), aging between the first and second decade of life, and with
an infection in the nasal cavity (85.71%). Their main complaints were
nonspecific, such as foreign body sensation, nasal obstruction and epistaxis,
which decreased clinical suspicion (14.28%). Hemograms showed a high eosinophil
count (14.01%, ±13.73). The main morphological alterations found in
histopathological analysis were squamous metaplasia, mucosal hyperplasia,
vascular ectasia, and inflammatory infiltration. Conclusions: In our country, little is known
about the pathogenesis of rhinosporidiosis, and it is easily confused with
other pathologies. However, our cases have shown a series of morphological
alterations that can be helpful to histopathological diagnosis and are poorly
described in the literature.
Author (s) Details
Antonio Augusto
Postgraduate Program in Adult Health (PPGSAD), Federal University of Maranhão, São Luís, Maranhão, Brazil.
Francílio Araújo Almeida,
Laboratory of Immunofluorescence and Electron Microcopy (LIME), Presidente Dutra University Hospital, Federal University of Maranhão, São Luís, Maranhão, Brazil.
José de Ribamar Castro Veloso,
Department of Pathology, Presidente Dutra University Hospital, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Jaqueline Diniz Pinho,
Laboratory of Immunofluorescence and Electron Microcopy (LIME), Presidente Dutra University Hospital, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Antonio de Deus Filho,
Federal University of Piauí, Teresina, Piauí, Brazil.
Joyce Santos Lages,
Department of Public Health, Presidente Dutra University Hospital, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Gyl Eanes Barros Silva,
Department of Pathology, Ribeirão Preto Medical School – University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
View Book: - http://bp.bookpi.org/index.php/bpi/catalog/book/190
Author (s) Details
Antonio Augusto
Postgraduate Program in Adult Health (PPGSAD), Federal University of Maranhão, São Luís, Maranhão, Brazil.
Francílio Araújo Almeida,
Laboratory of Immunofluorescence and Electron Microcopy (LIME), Presidente Dutra University Hospital, Federal University of Maranhão, São Luís, Maranhão, Brazil.
José de Ribamar Castro Veloso,
Department of Pathology, Presidente Dutra University Hospital, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Jaqueline Diniz Pinho,
Laboratory of Immunofluorescence and Electron Microcopy (LIME), Presidente Dutra University Hospital, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Antonio de Deus Filho,
Federal University of Piauí, Teresina, Piauí, Brazil.
Joyce Santos Lages,
Department of Public Health, Presidente Dutra University Hospital, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Gyl Eanes Barros Silva,
Department of Pathology, Ribeirão Preto Medical School – University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
View Book: - http://bp.bookpi.org/index.php/bpi/catalog/book/190
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