Reflection of Challenges in Blood Safety Practices: An Overview | Chapter 1 | New Advances in Medicine and Medical Science Vol. 2

 Whole blood accumulation has increased in past 10 years but it has abandoned to keep in pace with the raised demand. Nation’s blood safety has enhanced with 99% of whole blood gifts obtained from voluntary non-rewarded donors. Nevertheless, unmet clinical demand for ancestry along with the augmented occurrence of human immunodeficiency virus and syphilis usually population possess new challenges to transference services. To confirm a safe, efficacious in addition to appropriate adequate blood supply, neverending efforts are needed to recruit and hire adequate number of voluntary ancestry donors [low-risk] and again efforts should should for efficacious donor prescreening, ancestry testing procedure, invigorating patient blood management accompanying Hospital transfusion committee of the Hospital.

Author(s) Details:

Subhashis Das,
Department of Pathology, Sri Devaraj Urs Academy of Higher Education and Research (SDUAHER), Tamaka, Kolar, Karnataka, India.

Nikhil,
Department of Pathology, Sri Devaraj Urs Academy of Higher Education and Research (SDUAHER), Tamaka, Kolar, Karnataka, India.

Gaurav Khichariya,
Thyro-Care, Raipur, Chhattisgarh, India.

T. Amrutha,
Department of Pathology, Sri Devaraj Urs Academy of Higher Education and Research (SDUAHER), Tamaka, Kolar, Karnataka, India.

Snigdha Sinha,
Department of Pathology, Sri Devaraj Urs Academy of Higher Education and Research (SDUAHER), Tamaka, Kolar, Karnataka, India.

Please see the link here: https://stm.bookpi.org/NAMMS-V2/article/view/10619

Hazards of Platelet Transfusion | Chapter 5 | Research Advances in Microbiology and Biotechnology Vol. 5

 Introduction: Antibody screening followed by nucleic acid amplification techniques in blood donor screenings have decreased nowadays but bacterial contamination still remains a key problem in Blood banking. Particularly platelets are affected due to constant suitable environment for bacteria to grow such as storage temperature and composition of platelet concentrates.

Materials and Methods: Various methods are implied to evaluate contaminated platelet units. Quantitative/qualitative assessment by number of Colony forming units infused ,swirling phenomenon and microscopic evaluation of blood and its components and measurement of pCO2, pO2 , pH , glucose concentration. Other methods of evaluation are BacT/Alert (BioMerieux) and eBDS (Pall) were utilized nowadays for to detect bacterial contamination. For ultrafast and specific results, molecular technologies, based on the detection of ribosomal RNA of a wide variety of bacteria in a platelet contaminated sample containing 1–10 CFU/mL, have also been evaluated but molecular techniques are expensive. Pathogen reduction techniques is helpful as they make bacteria and viruses inactive in the contaminated platelet concentrates. Two most common methods are generally utilized for inactivation of platelets are psoralen and riboflavin-based method.

Results and Conclusion: Institute has to establish their own measures to decrease the possible platelet concentrates contamination. Pathogen inactivation techniques will be the next revolutionary aspect in blood banking.

Author(s) Details:

Subhashis Das,
Department of Pathology, Sri Devaraj Urs Academy of Higher Education and Research (SDUAHER), Tamaka, Kolar, Karnataka, India.

Nikhil,
Department of Pathology, Sri Devaraj Urs Academy of Higher Education and Research (SDUAHER), Tamaka, Kolar, Karnataka, India.

Gaurav Khichariya,
Thyro-care, Raipur, Chhattisgarh, India.

T. Amrutha,
Department of Pathology, Sri Devaraj Urs Academy of Higher Education and Research (SDUAHER), Tamaka, Kolar, Karnataka, India.

Snigdha Sinha,
Department of Pathology, Sri Devaraj Urs Academy of Higher Education and Research (SDUAHER), Tamaka, Kolar, Karnataka, India.

Please see the link here: https://stm.bookpi.org/RAMB-V5/article/view/10483