Skincare Products – A Risky Path | Chapter 17 | Recent Developments in Medicine and Medical Research Vol. 1

 The human integumentary system's largest organ, skin interacts with the environment and protects the body from viruses and hazardous chemicals. It comes into contact with the environment in daily life, either directly or indirectly, through a variety of sources, such as skincare products available on the market. We examine a list of a few substances that have been demonstrated to alleviate skin ailments while simultaneously causing serious acute diseases in this study. Sodium lauryl sulphate, diethanolamine, nanoparticles (zinc oxide, titanium oxide), monoethanolamine, triethanolamine, propylene glycol, and butylene glycol are all found in most skin care products and have both good and negative effects. The primary goal of this research is to shed light on skincare products that include chemicals that have been demonstrated to be hazardous to the human body.

Author(S) Details

Atefa Noorain
Thomson Reuters, India.

View Book:- https://stm.bookpi.org/RDMMR-V1/article/view/4088

Development of a Discriminatory Drug Dissolution Method for Estimation of Rivaroxaban from Rivaroxaban Tablets | Chapter 9 | Current Aspects in Pharmaceutical Research and Development Vol. 2

 The purpose of this study is to develop a discriminate dissolving method that may be utilised as a release parameter for testing and assessing product performance in regulated markets utilising quality by design trials. Dissolution testing is required for all solid oral dosage forms and is utilised for product release and stability testing throughout the development life cycle. The proper parameters were developed after testing solubility in the dissolution medium, surfactant concentration, rotation speed, dissolution medium pH, and apparatus type. The best dissolution conditions were found using a USP apparatus II, 900 ml of 0.4 percent SLS medium in pH 4.5 acetate buffer, and a 75 rpm rotation speed, according to research. Conclusion: This study demonstrates the methodical development of a discriminate dissolution method for Rivaroxaban, a BCS Class 2 medication with pH-independent solubility. The dissolution method described here can be used to perform a quality control test on Rivaroxaban tablets, with an emphasis on batch to batch comparisons.

Author(s) Details        

Pankaj Mandpe
Micro Labs Ltd., Andheri (E), Mumbai, India.

View Book :- https://stm.bookpi.org/CAPRD-V2/article/view/3957