Thermodynamic Description of Living Homeostasis | Chapter 10 |New Insights into Physical Science Vol. 1

We studied the homeostatic equilibrium of the healthy organism. The homeostasis is controlled by oppositely effective physiologic feedback signal-pairs in various time-scales. We show that the entropy of every signal in this state is identical and constant: SE=1.8. The controlling physiological signals fluctuate around their average values. The fluctuation is time-fractal, (pink-noise), which characterizes the homeostasis. The aging is the degradation of the competing pairs of signals, decreasing the complexity of the organism. This way, the color of the noise gradually changes to brown. A special scaling process occurs during the aging: the exponent of the frequency dependence of the power density function grows in this process from 1 to 2, but the homeostasis of the system is unchanged.

Author (s) Details

Yu-Cheng Lin
Graduate Institute of Electronic Engineering, Ming Chung University, Taoyuan, Taiwan.

Yi-Chi Chen
R&D Department, Ampire Co. Ltd., New Taipei City, Taiwan.

Liang-Yu Chen
Graduate Institute of Biological Technology, Ming Chung University, Taoyuan, Taiwan.

View Book :-  http://bp.bookpi.org/index.php/bpi/catalog/book/193

Surface Modification of Sulfide for QCM Based Protein Biosensor | Chapter 12 | New Insights into Physical Science Vol. 1

The rapid development of surface sensitive biosensor technologies requires optimum control of surface modification to provide reliable and reproducible results. To assemble a quartz crystal microbalance (QCM)-based protein biosensor, we focused our attention on the sulfide receptor and its integration with the surface of the golden electrode. Here, we present different surface modification processing time to allow sulfide molecules to be immobilized to a gold-coated sensor for QCM sensing. The surface modification was also tested with bovine serum albumin (BSA) binding measurement. The optimum surface modification processing time was obtained according to the experiment.

Author(s) Details

Yu-Cheng Lin 
Graduate Institute of Electronic Engineering, Ming Chung University, Taoyuan, Taiwan

Yi-Chi Chen
R&D department, Ampire Co. Ltd., New Taipei City, Taiwan

Liang-Yu Chen
Graduate Institute of Biological Technology, Ming Chung University, Taoyuan, Taiwan.

View Book :- http://bp.bookpi.org/index.php/bpi/catalog/book/193