Evaluation of Schiff Bases Derived from 1,8-diaminonaphtalène: An Approach towards Its Synthesis, Characterization and Biological Activities | Chapter 7 | Current Topics and Emerging Issues in Chemical Science Vol. 2

 This episode evaluates the synthesis, Characterization and Biological Activity of Schiff Bases arisen 1,8-diaminonaphtalène.  Schiff bases are the most usual organic compounds. They have existed proved to exhibit a broad range of biological projects, including antifungal, completely clean, antimalarial, antiproliferative, anti-angering, antiviral, and antipyretic properties. Salicylaldehyde, Ortho-Vanilline, and benzene-1,8-diaminonaphtalene were acquired from Aldrich and used outside further purification. The compound have happened synthesized and from routine MS, IR and NMR spectrometry arrangements. The compounds are all active on bacterial strains other than Salmonella typhimirium, with a MIC profit of 7.5 mg / mL. They show a percentage of antagonistic-radical activity of 75.476 ± 5.070 for the compound DAN-S and of 68.142 ± 6.539 for the compound DAN-OV. The less substituted DAN-S compound is more alive as shown in the graph resembling pie. For these molecules, this is the first occasion, our information, that such main antioxidant properties have happened observed.

Author(s) Details:

Kangah Niameke Jean Baptiste,
Laboratoire de Thermodynamique et de Physico-Chimie du Milieu, UFR SFA, Universite Nangui Abrogoua, Abidjan, Cote d’Ivoire.

Tuo Nanou Tieba,
Laboratoire de Thermodynamique et de Physico-Chimie du Milieu, UFR SFA, Universite Nangui Abrogoua, Abidjan, Cote d’Ivoire.

Ballo Daouda,
Laboratoire de Chimie Organique Heterocyclique URAC 21, Pole de Competence Pharmacochimie, Faculte des Sciences, Universite’ Mohammed V, Rabat, Morocco and Laboratoire de Constitution et Reaction de la Matiere (LCRM), UFR Sciences des Structures de la Matiere et Technologie, Universite Felix Houphouet-Boigny, Abidjan, Cote d’Ivoire.

Kablan Ahmont Landry Claude,
UFR Des Sciences Biologiques, Universite Peleforo Gon Coulibaly de Korhogo, Korhogo, Cote d’Ivoire.

Kouame N’goran Etienne,
Laboratoire de Thermodynamique et de Physico-Chimie du Milieu, UFR SFA, Universite Nangui Abrogoua, Abidjan, Cote d’Ivoire.

Kodjo Charles Guillaume,
Laboratoire de Thermodynamique et de Physico-Chimie du Milieu, UFR SFA, Universite Nangui Abrogoua, Abidjan, Cote d’Ivoire.

Ziao Nahosse,
Laboratoire de Thermodynamique et de Physico-Chimie du Milieu, UFR SFA, Universite Nangui Abrogoua, Abidjan, Cote d’Ivoire.

Please see the link here: https://stm.bookpi.org/CTEICS-V2/article/view/11533