Saturday, 5 August 2023

Experience of Pediatric Teratomas in Uncommon Sites in a Tertiary Centre | Chapter 5 | Current Progress in Medicine and Medical Research Vol. 6

 Introduction: In pediatric surgical practice, teratomas in organs and sacrococcygeal areas are somewhat common neoplasms. Teratomas in extragonadal sites are exceptional, with various clinical lineaments and variable organic behavior.Aim: The aim of the study was to comment the prevalence of pediatric teratomas in nonconforming sites, clinical performance, and histological variation.Materials and Methods: This anticipated observational study was completed activity for 5 years from January 2017 to December 2022 in the Department of Pathology in a after second care hospital together with Department of Pediatric Surgery. 119 cases of pediatric teratoma were resolved in the Department of Pathology of which 42 cases were at nonconforming sites. Clinical parameters like past taking and appropriate clinical test, imaging studies and routine investigations were all accomplished according to the proforma. The removed specimens were taken. Sections from various regions of the tumor was endured. The paraffin embedded fabric blocks were subsequently tainted for H&E followed by histopathological newsgathering.Results and Analysis: A total of 119 cases of pediatric teratomas were recorded, of that, 42 cases were teratoma of atypical station. This included, retroperitoneal teratoma (14 cases), sacrococcygeal teratoma (13 cases), stomachic teratoma (3 cases), cervical teratoma (1 case), pulmonary teratoma (1 case), adrenal teratoma (2 cases), floor of the mouth (1 case), organ meat (1 case), kidney (2 cases), abdominal divider (1 case), oral crater (2 cases) and mesentery (1 case). Retroperitoneum and sacrococcyx were the commonest exceptional sites.Conclusion: Meticulous search for the young or malignant component concede possibility be instituted as it helps in healing decisions. Early disease influences clinical conclusion and management, providing a better consequence. Continued follow-up (accompanying alpha-fetoprotein and radiology) to exclude recurrence. More effective antenatal hide, for early diagnosis and management, to lower the risk of malignant conversion, hence better forecast.

Author(s) Details:

Chhanda Das,
Pathology, IPGME&R, Kolkata, West Bengal, India.

Madhumita Mukhopadhyay,
Pathology, IPGME&R, Kolkata, West Bengal, India.

Ankita Pranab Mandal,
Department of Pathology, Haldia Sub-divisional Hospital, Haldia, Purba Medinipur, West Bengal, India.

Biswanath Mukhopadhyay,
Apollo Gleneagles Hospitals, Kolkata, West Bengal, India and Pediatric Surgery, NRS Medical College, Kolkata, West Bengal, India.

Ashis Kumar Saha,
Department of Health and Family Welfare, Medical Education Services, West Bengal, India.

Please see the link here: https://stm.bookpi.org/CPMMR-V6/article/view/11477

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