Friday, 16 June 2023

The Potential of Terminalia chebula Aqueous Extract in Plasmid Curing Activity against R-plasmids of Microorganisms | Chapter 13 | Novel Aspects on Pharmaceutical Research Vol. 3

 From distant past, humans are benefited from usual drugs based on curative plant formulations. They are known to have preventive and helping cure abilities for various conditions. Antimicrobial resistance happens due to the mutation in microorganisms and the unfit use of antibiotics. The use of plasmid-curing powers in combination accompanying antibiotics may comprise a solution to control the development and spread of medicine resistance encrypted by antibiotic resistance plasmids. In this unit, we describe the plasmid curing venture of the protein-enriched aqueous extract from the crop of Terminalia chebula against multi-drug resistance microorganisms Bacillus subtilis and Shigella sonnei. The partially purified extract healed plasmids pUB110 and pARI-815 of B. subtilis and S. sonnei at 100% and 44% curing efficiency, individually, which was again checked by the agarose coagulate electrophoresis.

Author(s) Details:

Pratibha Srivastava,
MACS-Agharkar Research Institute, Pune-411004, Maharashtra, India.

Prashant K. Dhakephalkar,
MACS-Agharkar Research Institute, Pune-411004, Maharashtra, India.

Please see the link here: https://stm.bookpi.org/NAPR-V3/article/view/10888

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